Detalhe da pesquisa
1.
Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists.
Talanta
; 275: 126104, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38677166
2.
Novel TLR4-Activating Vaccine Adjuvant Enhances the Production of Enterococcus faecium-binding Antibodies.
J Med Chem
; 67(7): 5603-5616, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38513080
3.
Cleaner synthesis of preclinically validated vaccine adjuvants.
Front Chem
; 11: 1252996, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38025058
4.
Overcoming Challenges in Chemical Glycosylation to Achieve Innovative Vaccine Adjuvants Possessing Enhanced TLR4 Activity.
ACS Omega
; 8(39): 36412-36417, 2023 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37810727
5.
New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants.
J Med Chem
; 66(4): 3010-3029, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36728697
6.
Highly Selective SERCA2a Activators: Preclinical Development of a Congeneric Group of First-in-Class Drug Leads against Heart Failure.
J Med Chem
; 65(10): 7324-7333, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35580334
7.
Synthetic Glycolipids as Molecular Vaccine Adjuvants: Mechanism of Action in Human Cells and In Vivo Activity.
J Med Chem
; 64(16): 12261-12272, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34382796
8.
Increasing the Chemical Variety of Small-Molecule-Based TLR4 Modulators: An Overview.
Front Immunol
; 11: 1210, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32765484